Perspectives on the Pseudomonas aeruginosa Type III Secretion System Effector ExoU and Its Subversion of the Host Innate Immune Response to Infection
Pseudomonas aeruginosa is an opportunistic, Gram-negative pathogen and an important cause of hospital acquired infections, especially in immunocompromised patients.Highly virulent P.aeruginosa strains use a type III secretion system (T3SS) to inject exoenzyme effectors equi-jec 7 directly into the cytoplasm of a target host cell.P.aeruginosa strain