PERSPECTIVES ON THE PSEUDOMONAS AERUGINOSA TYPE III SECRETION SYSTEM EFFECTOR EXOU AND ITS SUBVERSION OF THE HOST INNATE IMMUNE RESPONSE TO INFECTION

Perspectives on the Pseudomonas aeruginosa Type III Secretion System Effector ExoU and Its Subversion of the Host Innate Immune Response to Infection

Pseudomonas aeruginosa is an opportunistic, Gram-negative pathogen and an important cause of hospital acquired infections, especially in immunocompromised patients.Highly virulent P.aeruginosa strains use a type III secretion system (T3SS) to inject exoenzyme effectors equi-jec 7 directly into the cytoplasm of a target host cell.P.aeruginosa strain

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